Faculty Profile
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Claude Meares
Professor of Chemistry Chemistry 190A Chemistry Building Office 752-0936 Lab cfmeares@ucdavis.edu |
Degrees:
1972 - PhD - Stanford University - Chemistry
1968 - BS - University of North Carolina - Chemistry
Department and Center Affiliations:
Chemistry Department
Cancer Center
Grad Group Affiliations and Specialties:
Biochemistry and Molecular Biology
Publications:
Corneillie TM, Lee KC, Whetstone PA, Wong JP, Meares CF. Irreversible Engineering of the Multielement-Binding Antibody 2D12.5 and Its Complementary Ligands. Bioconjugate Chem. 2004 Nov-Dec;15(6):1392-402.
Corneillie, Todd M.; Fisher, Andrew J.; Meares, Claude F.. Crystal Structures of Two Complexes of the Rare-Earth-DOTA-Binding Antibody 2D12.5: Ligand Generality from a Chiral System. Journal of the American Chemical Society 125(49), 15039-15048 (2003).
Marr MT, Datwyler SA, Meares CF and JW Roberts. 2001. Inaugural Article: Restructuring of an RNA polymerase holoenzyme elongation complex by lambdoid phage Q proteins. Proc Natl Acad Sci USA. 98(16):8972-8978
Chmura AJ, Orton MS and FC Meares. 2001. Antibodies with infinite affinity. Proc. Natl. Acad. Sci. USA. 98(15):8480-8484
Datwyler SA and CF Meares. 2000. Protein-protein interactions mapped by artificial proteases: where s factors bind to RNA polymerase. Trends in Biochemical Sciences. 25:408-414
Research Interests:
Most scientists know of our work with bifunctional chelating agents and engineered antibodies for the diagnosis and therapy of cancer. Although the medical applications occupy a large part of
Teaching Interests:
Application of chemical and physical approaches to biological and biomedical problems.