Faculty Profile
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Earl Sawai
Associate Adjunct Professor of Medical Pathology Pathology (School of Medicine) 3321 Tupper Hall Office 754-9860 Lab etsawai@ucdavis.edu |
Degrees:
1990 - PhD - Baylor College of Medicine - Molecular Virology
Grad Group Affiliations and Specialties:
Biochemistry and Molecular Biology
Genetics
Microbiology
Publications:
Sawai ET, S Hamza, M Ye, K Shaw, and PA Luciw.. 2000. Pathogenic Conversion of Live-attenuated Simian Immunodeficiency Virus (SIV) Vaccines is Associated with Expression of Truncated Nef . J Virol. 74:2038-2045
Sawai ET, IH Khan, PM Montbriand, BM Peterlin, C Cheng-Mayer, and PA Luciw. 1996. Activation of PAK by HIV and SIV Nef: Importance for AIDS in SIV-infected Rhesus Macaques. Curr Biol. 6:1519-1527
Khan IH, ET Sawai, E Antonio, CJ Weber, C Mandell, P Montbriand, and PA Luciw. 1998. Role of the SH3-ligand domain of Simian Immunodeficiency Virus Nef in interaction with Nef-associated kinase (NAK) and simian AIDS in rhesus macaques. J Virol. 72:5820-58
Research Interests:
A major focus of my lab is the biochemical characterization of the HIV/SIV regulatory gene product, Nef. Using a combined molecular biologic, biochemical, and virologic approach, we are charac
Teaching Interests:
Molecular and biochemical virology. Retroviral pathogenesis. Regulation of signal transduction.