Faculty Profile

Ian Korf
Assistant Professor
Molecular and Cellular Biology (College of Biological Sciences)
Genome and Biomedical Sciences Facility / 4333
Office (530) 754-4989
Lab
ifkorf@ucdavis.edu
http://homepage.mac.com/iankorf
[Picture of Ian Korf]

Degrees:
1996 - PhD - Indiana University, Bloomington - Molecular, Cellular, and Developmental Biology
1989 - BA - Cornell University - Genetics

Awards:
NHGRI Genome Scholar and Faculty Transition Award

Department and Center Affiliations:
Genome Center

Grad Group Affiliations and Specialties:
Biochemistry and Molecular Biology
Genetics

Publications:
Ghedin E, Wang S, Spiro D, et al. (2007) Draft genome of the filarial nematode parasite Brugia malayi. Science. 317:1756-60

Parra G, Bradnam K, Korf I. (2007) CEGMA: a pipeline to accurately annotate core genes in eukaryotic genomes. Bioinformatics 9:1061-7.

Hajarnavis A, Korf I, Durbin R (2004). A probabilistic model of 3' end formation in Caenorhabditis elegans. Nucleic Acids Research 32:3392-3399.

Korf I (2004). Gene Prediction in Novel Genomes. BMC Bioinformatics 5:49.

Korf I (2003). Serial BLAST searching. Bioinformatics 19:1492-1496.

Korf I, Yandell M, Bedell J (2003). BLAST. O'Reilly & Associates, 360 pp

The Mouse Genome Sequencing Consortium (2002). Initial Sequencing and Comparative Analysis of the Mouse Genome. Nature 420:520-562.

Korf I, Flicek P, Duan D, Brent MR (2001). Integrating genomic homology into gene structure prediction. Bioinformatics Supplement 1:S140-148.

International Human Genome Sequencing Consortium (2001). Initial sequencing and analysis of the human genome. Nature 409:860-921.

Korf I, Gish W (2000). MPBLAST: improved BLAST performance with multiplexed queries. Bioinformatics 16:1052-1053.

Marth GT, Korf I, Yandell MD, Yeh RT, Gu Z, Zakeri H, Stitziel NO, Hillier L, Kwok PY, Gish WR (1999). A general approach to single-nucleotide polymorphism discovery. Nature Genetics 23:452-456.

Korf I, Fan Y, Strome S (1998). The Polycomb group in Caenorhabditis elegans and maternal control of germline development. Development 125:2469-2478.

Research Interests:
We are in an age of discovery, where identifying genes and their properties are established goals. In the future, we will enter an age of invention, where the goal will be to design genes with specific functions. The present and future of genomics requires a better understanding of molecular biology. My research seeks to improve our knowledge of genome structure and function by building accurate computational models from experimental data. Since genome modeling algorithms draw from fields such as speech recognition and text processing, my research is very much like reading the book of life.

Teaching Interests:


Computational molecular biology (sequence alignment, gene prediction, computer programming, databases, etc.)

Courses Taught:
MCB 182 Genomics and Bioinformatics - Term(s): Spring
GGG 201B Genomics - Term(s): Fall