Faculty Profile

Sheila David
Professor
Chemistry
Chemistry Bldg, Rm 312 Davis, CA 95616
Office +1 530 752 4280
Lab 530-752-1881
ssdavid@ucdavis.edu
http://www-chem.ucdavis.edu/
[Picture of Sheila David]

Degrees:
1989 - PhD - University of Minnesota - Chemistry
1984 - BA - Saint Olaf College - Chemistry

Awards:
Beckman Young Investigator
AP Sloan Foundation

Department and Center Affiliations:
Chemistry

Professional Societies:
American Chemical Society
Environmental Mutagen Society

Grad Group Affiliations and Specialties:
Biochemistry and Molecular Biology
Non-DBS Grad Group(s) - Chemistry

Publications:
"Unusual Structural Features of Hydantoin Lesions Translates into Efficient Recognition by Escherichia coli Fpg," Krishnamurthy, N., Muller, J.G., Burrows, C. J., David, S.S., Biochemistry, 2007, 46, 9355-9365.

"Base-excision repair of oxidative DNA damage, " David, S. S., O’Shea, V.L., Kundu, S., Nature, 2007, 447, 941-950.

"An Electron Trap for DNA-bound Repair Enzymes: A Strategy for DNA-mediated Signaling," Yavin, E., Stemp, E.D.A., O’Shea, V.L., David, S. S., Barton, J.K., Proc. Natl. Acad. Sci, USA, 2006, 103, 3610-3614.

"Insight into the Role of Tyrosine 82 and Glycine 253 in the Escherichia coli Adenine Glycosylase MutY, " Livingston, A.L., Kundu, S., Pozzi, M.H., Anderson, D.W., David, S. S., Biochemistry, 2005, 44, 14179-14190.

"A Role for Iron-Sulfur Clusters in DNA Repair,” Lukianova, O.A., David, S. S., Curr. Op. Chem. Biol., 2005, 9, 145-151.

Research Interests:
DNA repair chemical biology, base excision repair glycosylases, oxidative DNA damage repair, iron-sulfur proteins, nucleic acid enzymology

Laboratory Personnel:
370 Chemistry - Valerie O’Shea, Undergraduate student, 5/00-5/01, graduate student, 6/01-present Nirmala Krishnamurthy, Graduate Student, 6/03-present Sucharita Kundu, Graduate Student, 5/04-present Sheng Cao, Graduate Student, 4/04-present Lisa Ortgiesen, Graduate Student, 4/06-present Jody Richards, Graduate Student, 4/06-present Paige McKibbon, Graduate Student, 1/07-present Megan Brinkmeyer, Graduate Student, 1/07-present Benjamin Garman, Undergraduate Student, 3/07-present Zoe Smith, Undergraduate Student, 7/07-present Shon Chandra, Undergraduate Student, 7/07-present
http://chemgroups.ucdavis.edu/~david/

Teaching Interests:


Chemical Biology, Bioinorganic Chemistry, Bioorganic Chemistry, Organic Chemistry, Pharmaceutical Chemistry

Courses Taught:
Che 8A Elementary Organic Chemistry - Term(s): Fall
MCB 221A Physical Biochemistry - Term(s): Fall
Che 135 Advanced Bioorganic Chemistry Laboratory - Term(s): Spring
Che 221D Special Topics: Chemical Biology of Nucleic Acids