Faculty Profile

Andrew J. Fisher
Professor
Molecular and Cellular Biology (College of Biological Sciences)
Chemistry
4A Briggs Hall
Office 530-754-6180
Lab 530-752-5235
ajfisher@ucdavis.edu
http://www-crystal.ucdavis.edu/fisher
[Picture of Andrew J. Fisher]

Degrees:
1992 - PhD - Purdue University - Biophysics
1987 - BS - Purdue University - Biochemistry

Department and Center Affiliations:
Department of Chemistry
Department of Molecular and Cellular Biology

Grad Group Affiliations and Specialties:
Biochemistry and Molecular Biology
Biophysics
Cell and Developmental Biology
Non-DBS Grad Group(s) - Chemistry

Publications:
Ni, L., Chokhawala, H., Cao, H., Henning, R., Ng, L., Huang, S., Yu, H., Chen, X., and Fisher, A. J. (2007). Crystal structures of Pasteurella multocida sialyltransferase complexes with acceptor and donor analogs reveal substrate binding sites and catalytic mechanism. Biochemistry 46:6288-6298.

Yu, Z, Lemongello, D., Segel, I. H., and Fisher, A. J. (2008). Crystal structure of Saccharomyces cerevisiae 3´-Phosphoadenosine-5´-phosphosulfate (PAPS) Reductase complexed with adenosine 3´,5´-bisphosphate. Biochemistry In Press.

Tu, S.-L, Rockwell, N. C., Lagarias, J. C., and Fisher, A. J. (2007). Insight into the radical mechanism of phycocyanobilin:ferredoxin oxidoreductase (PcyA) revealed by X-ray crystallography and biochemical measurements. Biochemistry 46:1484-1494.

Yu, Z., Lansdon, E. B., Segel, I. H., and Fisher, A.J. (2007). Crystal structure of the Bi-functional ATP Sulfurylase/APS kinase from Chemolithotrophic Thermophile Aquifex aeolicus. J. Mol. Biol. 365:732-743.

Ni, L., Sun, M., Yu, H., Chokhawala, H., Chen, X., and Fisher, A. J. (2006). Cytidine 5'-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida. Biochemistry 45:2139-2148.

Forsyth, C., M., Lemongello, D., LaCount, D. J., Friesen, P. D., and Fisher, A. J. (2004). Crystal Structure of an Invertebrate Caspase. J. Biol. Chem. 279:7001-7008.

Research Interests:
Protein structure/function. Apoptosis. Sulfate activation. Phytochrome.
http://www-crystal.ucdavis.edu/fisher

Courses Taught:
Che 107A Physical Chemistry for the Life Sciences - Term(s): Fall
Che 217 X-ray Crystal Structure Determination - Term(s): Spring