Faculty Profile

Stuart Meyers
Professor
Anatomy, Physiology, and Cell Biology (Vet Med)
2319 Haring Hall
Office 530 752 9511
Lab 530-752-9938
smeyers@ucdavis.edu
http://faculty.vetmed.ucdavis.edu/faculty/smeyers/
[Picture of Stuart Meyers]
Cryopreservation and cryobiology of mammalian sperm. Mechanisms of spermatozoal cryoinjury.

Degrees:
1990 - Diploma - American College of Theriogenologists -
0 - DVM - Michigan State University - Veterinary Medicine
0 - PhD - University of California, Davis - Comparative Pathology
0 - MS - Oregon State University - Physiology
0 - BS - Michigan State University - Zoology

Department and Center Affiliations:
Center for Equine Health

Professional Societies:
American Society for Cell Biology
Society for the Study of Reproduction
Society for Theriogenology
Amercan College of Theriogenologists
American Association for the Advancement of Science
American Society of Andrology

Grad Group Affiliations and Specialties:
Cell and Developmental Biology
Molecular, Cellular, and Integrative Physiology
Non-DBS Grad Group(s) - Comparative Pathology

Publications:
Correa LM, Thomas A, Meyers SA. Reorganization of the Macaque Sperm Actin Cytoskeleton in Response to Osmotic Stress Contributes to Changes in Motility and Morphology. Biology of Reproduction, 2007. Papers in Press, published online ahead of print September 5, 2007. Biol Reprod 2007, 10.1095/biolreprod.107.060533.

Li MW, Meyers S, Tollner TL, Overstreet JW. Damage to Chromosomes and DNA of Rhesus Monkey Sperm Following Cryopreservation. Journal of Andrology 28: 493-501, 2007.

Baumber J, Meyers S. Changes in Membrane Lipid Order with Capacitation in Rhesus Macaque (Macaca mulatta) Spermatozoa. Journal of Andrology 27(4):578-87, 2006.

Ricker JV, Linfor JJ, Delfino WJ, Kysar P, Scholtz EL, Tablin F, Crowe JH, Ball BA, SA Meyers. Equine Sperm Membrane Phase Behavior: The Effects of Lipid-Based Cryoprotectants. Biology of Reproduction 74, 359-365 (2006)

Enders AC, Douglas GC, Meyers SA, VandeVoort CA. Interactions Of Macaque Blastocysts With Epithelial Cells In Vitro. Human Reproduction 20(11):3026-3032, 2005

Ali Honaramooz, Ming-Wen Li, M. Cecilia T. Penedo, Stuart Meyers, and Ina Dobrinski. Accelerated Maturation of Primate Testis by Xenografting into Mice. Biol Reprod 70: 1500-1503, 2004 .

Rutllant JL, Pommer AC, Meyers SA. Osmotic tolerance limits and properties of rhesus monkey (Macaca mulatta) spermatozoa. Journal of Andrology24: 534-541, 2003.

Baumber J, Ball BA, Linfor JJ, Meyers SA. Reactive Oxygen Species and Cryopreservation Promote DNA Fragmentation in Equine Spermatozoa. Journal of Andrology, Vol. 24, No. 4, July/August 2003

Pommer AC, Rutllant J, Meyers A. Phosphorylation of Protein Tyrosine Residues in Fresh and Cryopreserved Stallion Spermatozoa under Capacitating Conditions. Biology of Reproduction 68, 12081214 (2003)

Linfor JJ, Meyers SA. Assessing DNA Integrity of Cooled and Frozen-Thawed Equine Sperm Using Single Cell Gel Electrophoresis. J Androl. 2002 Jan-Feb;23(1)107-113.

Research Interests:
Research in our laboratory has centered on optimization of gamete cryopreservation and development of new methods for preservation of male gametes. Alternative modes of sperm preservation beyond refrigeration and cryopreservation need to be developed for the efficient storage of genetically defined individuals or endangered species. We are working with both the non-human primate and the horse. These are two species for which individual male variation plays an important role in developing a cryopreservation protocol that can be successfully used for all males. Our goals are to first to develop an understanding of fundamental mechanisms of cellular damage caused by low temperature storage, and then to use this knowledge to develop new methods for gamete preservation.  We use the techniques of lipid analysis, flow cytometry and confocal, fluorescence, and electron microscopy to evaluate the integrity of sperm cell organization and cell function.
http://www.vetmed.ucdavis.edu/apc/MeyersLab/Labsite 03/index.html

Laboratory Personnel:
Meyers Laboratory - Megan McCarthy, BS, MS/Staff Research Assistant Victoria Burruel, PhD/ Staff Research Assistant Julie Cole Shacosky, DVM, Diplomate ACT, Graduate Student Shiho Sumigama, DVM, Graduate Student Katie Klooster, BS, Graduate Student
www.vetmed.ucdavis.edu/apc/MeyersLab/Labsite%2003/index.html

Teaching Interests:


Reproductive Biology, Anatomy and Physiology of Reproductive Systems, Comparative Reproductive Physiology, Gross Anatomy of Locomotor System

Courses Taught:
VMD 401A Anatomy of the Locomotor System - Term(s): Fall
VMD 446 Reproduction System - Term(s): Winter
ANS 115 Horse Production - Term(s): Fall
PGG 220 General and Comparative Physiology of Reproduction - Term(s): Spring
VMD 432 Gastrointestinal System - Term(s): Winter
VMD 402D Anatomy and Physiology of Urinary System - Term(s): Spring