Faculty Profile

Jinoh Kim
Assistant Professor
Pediatrics (School of Medicine)
MIND Institute Wet Lab 1421
Office 916-703-0451
Lab 916-703-0453
jinoh.kim@ucdmc.ucdavis.edu
[Picture of Jinoh Kim]

Degrees:
2000 - PhD - University of Connecticut - Biochemistry
1992 - MS - Seoul National University - Molecular Biology
1990 - BS - Seoul National University - Zoology

Department and Center Affiliations:
Pediatrics (School of Medicine)

Professional Societies:
The American Society of Cell Biology

Grad Group Affiliations and Specialties:
Cell and Developmental Biology

Publications:
Kim, S.D. and J. Kim. 2008. Sequence analyses of presenilin mutations linked to familial Alzheimer's disease. Cell Stress & Chaperones 13: 401-412.

Kim, J., B. Kleizen, R. Choy, G. Thinakaran, S.S. Sisodia and R. Schekman. 2007. Biogenesis of gamma secretase early in the secretory pathway. J. Cell Biol. 179: 951-963.

Kim, J., A. Thanabalasuriar, T. Chaworth-Musters, J.C. Fromme, E. Frey, P. Lario, P. Metalnikov, K. Rizg, Ni. Thomas, S.F. Lee. E.L. Hartland, P.R. Hardwidge, T. Pawson, N. C. Strynadka, B.B. Finlay, R. Schekman, and S. Gruenheid. 2007. The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function. Cell Host & Microbe 2: 160-171.

Sun, C., S.L. Rusch, J. Kim, and D.A. Kendall. 2007. Chloroplast SecA and Escherichia coli SecA have distinct lipid and signal peptide preferences. J. Bacteriol. 189: 1171-1175.

Kim, J., S. Hamamoto, M. Ravazzola, L. Orci, and R. Schekman. 2005. Uncoupled packaging of amyloid precursor protein and presenilin 1 into COPII vesicles. J. Biol. Chem. 280: 7758-7768.

Kim, J., and Schekman, R. 2004. The ins and outs of presenilin 1 membrane topology. Proc. Natl. Acad. Sci. USA 101: 905-906.

Kim, J., S. Rusch, J. Luirink and D.A. Kendall. 2001. Is Ffh required for export of secretory proteins? FEBS Lett. 505: 245-248.

Kim, J., A. Miller, L. Wang, J. Müller, and D.A. Kendall. 2001. Evidence that SecB enhances the activity of SecA. Biochemistry 40: 3674-3680.

Kim, J., and D.A. Kendall. 2000. Sec-dependent protein export and the involvement of the molecular chaperone SecB. Cell Stress & Chaperones 5: 267

Kim, J., J. Luirink, and D.A. Kendall. 2000. SecB dependence of an exported protein is a continuum influenced by the characteristics of the signal peptide or early mature region. J. Bacteriol. 182: 4108-4112.

Kim, J., and D.A. Kendall. 1998. Identification of a sequence motif that confers SecB dependence on a SecB-independent secretory protein in vivo. J. Bacteriol. 180: 1396-1401.

Chen, H., J. Kim, and D.A. Kendall. 1996. Competition between functional signal peptides demonstrates variation in affinity for the secretory pathway. J. Bacteriol. 178: 6658-6664. (Chen and Kim contributed comparably to this work).

Research Interests:
My laboratory is interested in mechanisms of protein export from the endoplasmic reticulum (ER) and human diseases caused by ER export defects.

Laboratory Personnel:
Intracellular Protein Trafficking Lab - Sun Don Kim, Joonsik Yoon
http://www.ucdmc.ucdavis.edu/mindinstitute/ourteam/faculty_staff/jkim.html

Teaching Interests:


Cell Biochemistry (MCB221D)