UC Davis Genome Center
 
John C. Rutledge
Professor and Chief
Internal Medicine: Division of Endocrinology, Clinical Nutrition and Vascular Medicine (School of Medicine)
Genome and Biomedical Sciences Facility
Office 530-752-4713
Lab 530-752-2812
jcrutledge@ucdavis.edu
 
Vascular biology, vascular inflammation, diabetic vasculopathy, lipoproteins, gender effects on the vascular wall pathology, maternal-fetal imprinting

Degrees:
1976 - MD - - Baylor College of Medicine -
1972 - BA - University of Texas - Biology

Awards:
Richard A. and Nora Eccles Harrison Endowed Chair in Diabetes Research
Dean's Award for Excellence in Mentoring

Department and Center Affiliations:
Genome Center
Center for Biophotonics Science and Technology
General Clinical Research Center
Foods for Health Institute

Grad Group Affiliations and Specialties:
Molecular, Cellular, and Integrative Physiology
Non-DBS Grad Group(s) - Nutritional Sciences

Publications:
Mullick AE, Powers AF, Kota RS, Tetali SD, Eiserich JP, Rutledge JC. Apolipoprotein E3- and nitric oxide- dependent modulation of endothelial cell inflammatory responses. Arterioscler Thromb Vasc Biol 2007;27(2):339-345.

Motton DD, Keim NL, Tenorio FA, Horn WF, Rutledge JC. Postprandial monocyte activation in response to meals with high and low glycemic loads in overweight women. Am J Clin Nutr 2007;85:60-65.

Eiselein L, Wilson D, Lame M. Rutledge JC. Lipolysis products from triglyceride-rich lipoproteins increase endothelial permeability, perturb zonula occludens-1, F-actin, and induce apoptosis. Am J Physiol Heart Circ Physiol 2007 Jan 26;[Epub ahead of print]

Research Interests:
  • Vascular biology
  • Atherogenesis
  • Diabetic vasculopathy
  • Lipoprotein-vascular wall interactions
  • Female sex hormones and the vascular wall


Laboratory Personnel:
Rutledge Laboratory - Adam Mullick, Larissa Eiselein, Richard Fitch, Laura Higgins, Fatima Tenorio, Andy Powers, Sam Zaid, Harras Zaid, Roth Mea, Rama Kota, Deborah Motton

Teaching Interests:


  • Scientific proposal writing workshop
  • Endocrinology (IMD420F)