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Degrees: 1989 - PhD - University of Buenos Aires - Biochemistry 1985 - Diploma - University of Buenos Aires - Biochemistry Department and Center Affiliations: Molecular Biosciences, School of Veterinary Medicine; Member of the UC Davis Cancer Center Professional Societies: American Society for Biochemistry and Molecular Biology Society for Free Radical Research Grad Group Affiliations and Specialties: Biochemistry and Molecular Biology Publications: Giulivi, C., Ross-Inta, C.M., Horton, A., and Luckhart, S. (2008) Metabolic Pathways in Anopheles stephensi mitochondria. Biochem. J., in press. Ross-Inta, C., Tsai, C.-Y., and Giulivi, C. (2008) The mitochondrial pool of free amino acids reflects the composition of mitochondrial-DNA encoded proteins: Indication for a post-translational quality control for protein synthesis. Biosci. Reports, in press. DiMarco, T. and Giulivi, C. (2007) Evaluation of analytical methods to detect dityrosine, a biomarker of oxidative stress, in biological samples. Mass Spec. Rev. 26, 108-120. Miller, S., Inta-Ross, C. and Giulivi, C. (2007) Kinetic and proteomic analyses of S-nitrosoglutathione-treated hexokinase: consequences for cancer energy metabolism. Amino acids 32, 593-602. Giulivi, C., Kato, K. And Cooper, C. E. (2006) Nitric oxide regulation of mitochondrial oxygen consumption I: cellular physiology. Am. J. Physiol. 291, 1225-1231. Cooper CE and Giulivi, C. (2007) Nitric oxide regulation of mitochondrial oxygen consumption II: molecular mechanism and tissue physiology. Am J Physiol. 292, 1993-2003. Kato K, Giulivi C. (2006) Critical overview of mitochondrial nitric-oxide synthase. Front Biosci. 11:2725-38. Mazzanti, R. and Giulivi, C. (2006) Coordination of nuclear- and mitochondrial-DNA encoded proteins in cancer and normal colon tissues. Biochim Biophys Acta 1757, 618-623. Mazzanti, R., Solazzo, M. Squires, R., Fantappie, O., Cechi, F, Bianchi, P., and Giulivi, C. (2006) Differential expression proteomics of human colon cancer. Am J Physiol 290:G1329-38. Green, A., Rutherford, M. S., Regal, R. R., Flickinger, G. H., Hendrickson, J. A., Giulivi, C., Mohrman, M. E., Fraser, D. G., and Regal, J. F. (2005) Arginase Activity Differs with Allergen in the Effector Phase of Ovalbumin- versus Trimellitic Anhydride-Induced Asthma. Tox. Sci. 88, 420-433. Johnson F, Giulivi C. (2005) Superoxide dismutases and their impact upon human health. Mol Aspects Med. 26, 340-352. Oursler, M. J., Bradley, E., Elfering, S. and Giulivi, C. (2005) Native, not nitrated, cytochrome c and mitochondrial-derived hydrogen peroxide drive osteoclast apoptosis. Am., J. Physiol. 288, C156-168. Haynes, V., Elfering, S. L., Squires, R., Traaseth, N., Solien, J., Ettl , A. and Giulivi, C. (2004) Mitochondrial Nitric-Oxide Synthase: Role in Pathophysiology. IUBMB Life 55, 599-603. Traaseth, N, Elfering, S. L., Solien, J., Haynes, V., and Giulivi, C. (2004) Role of Calcium Signaling in the Activation of Mitochondrial Nitric-Oxide Synthase and Citric Acid Cycle. Biochim. Biophys. Acta 1658, 64-71. Haynes, V., Elfering, S. L., Traaseth, N., and Giulivi, C. (2004) Mitochondrial Nitric-Oxide Synthase: Enzyme expression, characterization and regulation. J. Bioenerg. Biomemb. 36, 341-346. Elfering, S. L., Haynes, V., Traaseth, N., Ettl, A. and Giulivi, C. (2004) Aspects, mechanism, and biological relevance of mitochondrial protein nitration sustained by mitochondrial nitric oxide synthase. Am. J. Physiol. 286, H22-H29. Xiong, S., She, H., Takeuchi, H., Engelhardt, J. F., Barton, C. H., Zandi, E., Giulivi, C., and Tsukamoto, H. (2003) Signaling role of intracellular iron in NF-kB activation. J. Biol. Chem. 278, 17646-54. Giulivi, C. (2003) Characterization and function of mitochondrial nitric-oxide synthase. Free Radical Biol. Med. 34, 397-408. Giulivi, C, Traaseth, N. J., and Davies, K. J. A. (2003) Tyrosine oxidation products: analysis and biological relevance. Amino Acids 25, 227-232. Elfering, S. L., Sarkela, T. M. and Giulivi, C. (2002) Biochemistry of mitochondrial nitric oxide synthase. J. Biol. Chem. 277, 38079-38086. Sarkela, T., Berthiaume, J., Elfering, S., Gybina, A. and Giulivi, C. (2001) The modulation of oxygen radical production by endogenous nitric oxide in mitochondria. J. Biol. Chem. 276, 6945-6949. Steffen, M., Sarkela, T.M., Gybina, A.A., Steele, T.W., Traaseth, N. J., Kuehl, D. and Giulivi, C. (2001) Metabolism of S-nitrosoglutathione in intact mitochondria. Biochem. J. 356, 395-402. French, S., Giulivi, C., and Balaban, R. S. (2001) Nitric oxide synthase in porcine heart mitochondria: Evidence for a low physiological activity. Am. J. Physiol. 280, H2863-7. Research Interests: -Biosynthesis of nitric oxide in mitochondria. Role of nitric oxide produced by mitochondria in cellular oxygen metabolism and vasodilation. Mitochondrial nitric oxide synthase: regulation of expression. Biosynthesis and metabolism of endogenous nitric oxide in mammalian cells. Role of nitric oxide, superoxide anion, and peroxynitrite anion in mediating pathophysiological processes. -Mitochondrial nitrated proteins: role of nitration, metabolism of nitrated proteins, implications for pathophysiology. -Oxygen and nitrogen free radical biochemistry and chemistry in in vitro and in vivo model systems. Mechanistic aspects of oxygen and nitrogen free radical damage. -Proteomics of aging and oxidative damage of mitochondria -Functional proteomics of human colon cancer Laboratory Personnel: 2116 Haring Hall - Ms. Catherine Ross-Inta, Yi-Fan Zhang, Jennifer Pong, Julia Overman, Sarah Wong Teaching Interests:Biological Chemistry; Spectroscopy; Bioenergetics; Oxygen and nitrogen free radical biochemistry. Courses Taught: PTX 290 Seminar - Term(s): Spring VM 403 Physiological Chemistry - Term(s): Fall |
![[Picture of Cecilia Giulivi]](/FacultyProfiles/Common/PersonalImages/1996.jpg)