Students
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Name: Jennifer Bratt
Major Professor: Jerold Last Department: Internal Medicine: Pulmonary/Critical Care Division (School of M Lab Phone: 752-0674 Email: jmbratt@ucdavis.edu |
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Degrees
BS - University of California, Davis - Genetics - Year Not Specified | |
| Research Interests | |
| I am interested in the effects of altered arginine metabolism in inflammatory diseases such as atherosclerosis and asthma. Arginase can regulate nitrc oxide production through substrate limitation. How does the temporal up-regulation of arginase affect leukocyte recruitment, cytokine production, and tissue remodeling in chronic inflammatory disease? | |
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Publications
Mansoor JK, Decile KC, Giri SN, Pinkerton KE, Walby WF, Bratt JM, Grewal H, Margolin SB, Schelegle ES. Influence of pirfenidone on airway hyperresponsiveness and inflammation in a Brown-Norway rat model of asthma.Pulm Pharmacol Ther. 2007;20(6):660-8. Kenyon NJ, Bratt JM, Linderholm AL, Last MS, Last JA.Arginases I and II in lungs of ovalbumin-sensitized mice exposed to ovalbumin: sources and consequences.Toxicol Appl Pharmacol. 2008 Aug 1;230(3):269-75. | |